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File: 123096_sep96_decls7_0008.txt
Subject: PREVENTION AND TREATMENT OF NERVE AGENT POISONING
Unit: VAR. BUMED
Parent Organization: BUMED
Box ID: BX303902
Folder Title: PREVENTION AND TREATMENT OF NERVE AGENT POISONING
Document Number: 1
Folder Seq #: 14
UNCLASSIFIED
FM$-285tNAVMED P-5041/AFM 160-11
dostigmine bromide tablets (21 total) which are ing the NAPP and safeguarding it against loss.
packaged in a blister pack. Each blister pack Service members will secure the blister pack in the
(NAPP) contains enough tablets for 7 days (1 taken sleeve or breast pocket of the chemical protective
every 8 hours). ensemble (or in another part of the ensemble, as
directed by local standing operating procedure
(SOP)).
MINE PRMFATMEI NOTE
In conjunction with the NAPP, service
(KAPP)
"EN ORDERED By YOUA 001 members should be issued an additional
M268AIo Sk-m Deconta g- Kit--tfig
THE STATED DOSE G-1) which will be carried on the load-
MINE BROMIDE X 21 TABLETS bearing equipment suspenders.
c. Orders to start taking the NAPP will be issued
of com-
mand.
d- Resupply will be provided by Combat, Combat
Support, and Combat Service Support Units.
2-17. Effects of Pyridostigmine Bromide
a. Pyridostigmine bromide protects an enzyme
(known as acetylcholinesterase) in the body from
the action of nerve agent& Muscles function as a
result of nerve impulses and the release of specific
SAM;-LE PYRIDOS'NGMINE BROMIDE TABLETS. -chemical substances. A chemical transmitter, ace-
tylcholine, acts at the neuromuscular junction
Figure2-2.NvwAi7i7uPymdostigmimPreireat,.te,,ITabletSeL (where the nerve interfaces with the muscle) (fig
2-3). When a nerve impulse reaches the neuromus-
b. Service members are initially issued I NAPP culir junction, acefylcholiiie'(the che-mical trans-
when the chemical protective ensemble is expected mitter) is released, thereby causing the muscle to
to be opened for use. They are responsible !or carry- contract. The enzyme, acetylcholinesterasd, stops
NEUROMC)SCULAR
JUNCTION
NERVE
d MUSCL6"
ELECTRICAL NERVE lq,
NERVE IMPULSE RELEASES
ACETYLCHOLINE
E CONTRACTS AND ACETYLCHOLINE
(CHEMICAL TRANSMITTER) IS INACNVATED By ACETYLCHOLINESTERASE
ACETYLCHOLINE CROSSES THE NEUROMUSCULAR
JUNCTION CAUSING MUSCLE CONTRACTION
Figure t-,q. S@atic nftrmus@rjuncti" (ml to scale).
2-16
UNCLASSIFIED,
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Document 11 f:/Week-44/BX303902/PREVENTION AND TREATMENT OF NERVE AGENT POISONING/prevention and treatment of nerve agent poisonin:1217960956196
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-44
Box ID = BX303902
Unit = VAR. BUMED
Parent Organization = BUMED
Folder Title = PREVENTION AND TREATMENT OF NERVE AGENT POISONING
Folder Seq # = 14
Subject = PREVENTION AND TREATMENT OF NERVE AGENT POISONIN
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 17-DEC-1996