PURIDOSTIGMINE BROMIDE PRETREATMENT FOR NERVE AGENTS

File: 970107_oct96_decls2_0002.txt
Page: 0002
Total Pages: 3

Subject: PURIDOSTIGMINE BROMIDE PRETREATMENT FOR NERVE AGENTS            

Unit: COMUSMARCENT

Parent Organization: COMUSCINCCEN

Box  ID: BX600093

Folder Title: FOLDER NAVAL MESSAGE FILES AUG  OCT 90 ARMY REFERRAL                                            

Document Number:          5

Folder Seq  #:         34





         IMMEDlAfE                       U N C L A S S I F I E D                 TOD        1341


         IF A DI$E  is MISSED,   D NOT 14AKE...IT UP.   DO NOT TAKE TWO (2)
         TABLETSIAT OTICE BECAUS@",DF A MISSED DOSE--START AGAIN WITH ONE
         TABLET VERY EIGIJ.T (8) @OURS. TAKING TWO (2) TABLETS AT ONCE COULD
         RESULT iii ADVERSE SIDE.'EFFECTS. CAUTION: TAKING MORE THAN ONE
         PAGE O3iRULSBUA$141 UNCA:AS
         TABLET AT A rl@IE DOES NOT PROVIte'ADi)ITIONAL PROTECTION. IN FACT
         IT MAY BE MORE HAZARDOUT IF     THERE  IS SUBSE(IUENT EXPOSREE TO NA
         WHEN THL'7 ORDER TO TAKE PYRIDOST16MINE IS GIVEN, IT SHOULD BE T@KEN
         USING THE ABOVE SCHEDUL4 PROVIDEO'.THE ENVIROPIMENT IS
         UNCONTAOINATED, INCLUD1446 THE HCURS OF DARKNESS, AND        EVEN THOUGH
         THE PROTECTIVE IIASKS IS:.WORN.
         6. SIGNt/SYMPTOIIS OF PY"PIDUSTIGNINE OVERDOSE AND ELLERGIC
         REACTIONS. Al-I'HOtJGH NO DETRIMENTAL EFFECTS ARE EXPECTED AT THE
         RECOMME6DED DOSAGE, DEP.@NT)ING ltl7L.ENGTH OF TIME AND AMOUNT OF
         MEDICATJC.tt4 TAKEN ALON(I @ITH INrilVIDIJAL PYYSIOLOGICAL VARIATIONS,
         CERTAIN'114DIVIDUALS MAi,,E)(PERIENOE THE FOLLOWING ADVERSE REACTIO@IS
         FROM PY@II)OSTIGMINE:    Agl)()Mlt4AL eRA141@S, NALJSEA, DIARRHEA, SKIN
         RASH, WEAKNESS, MUSCLE @R;,14PS, M@ISC'IJLAR TWITCHING AND/OR DiMNE@,., 6r:
         VISION Ott-' TO PINPOINTED PIJPILS.-'.[F ANY OF THESE SIGNS/SYMPTOKS



         PAGE 04'-RUFRSGG6313 UNCLAS:
         OCCUR, THE  SERVICE tqED-BgR @HOULD!CtiECK WITH MEDICAL      DEPARTMENT
         RLPRESENTATIVE.
         7. EMER4Ef4CY MEDICAL TR@ATMENT ADMINISTERED FOR PYRIDOSTIGMINE
         SIDE EFFECTS. ORDINARIL[S-DISCONTINUING PYRIDOSTIGMINE SHOULD
         BE ADEQPATE TO ALLEVIAT. SIGNS/SYMPTOMS. PYRIDOSTIGMINE MAY
         PERSIST:IN THE BLOOD FOR'24 HOURS, HOWEVER, AFTER BLOOD LEVELS
         PAGE 041RIlLSBUA8141 UNC4AS
         PEAK ItJ'@'FOUR (4) HOURSI'"EFFECTS  DIMINISH GRADUALLY. EMERGENCY
 INCLUDES ADMINISTERING   ATROPINE IN DOSES SUFFICIENT      TO
         OVERCOME THE CHOLINERGI@ CRISIS.-USE THE 2-Me ATROPINE
         AUTOINJECTOR. IF ADDITldf4AL ATROPINE IS REQUIRED, TWO (2) MG
         SHOULD BE -AI)MINISTERED-.b.Y MED DEPT REP EVERY FIFTEEN-TWENTY (15-20)
         MINUTES.' SEVERE CASES M4Y REQUIRE ASSISTED VENTILATION BUT WOULD
         BE lft4USIlAt. IF THE EIGHT.',(S) tiOUR'ADMINISTED DOSE HAD BEEN FOLLOWED.
         WHEN ST@SILIZED, THE:CAPUALTY 14AY NEED EVACUATION FOR FURTHER
         OBSERVARION AND TREATMEAT.
         S. USF.-DF PYlilf)OSTIGMINF
                                     PRETREATMENT IN AIRCREW PERSONNEL.
            A. A.' DIFZ[it,TION OF CORGNIZANT COMMANDER, ALL PERSONNEL INCLUDING
         DISI(iNAff-.'D AIRCREW WIL(.;TAKE PYRIDOSTIGMINE AS OUTLINED INNPREVIOUS-'.'
         PARAS.



         PA@E 05 RLIFrisGG6313 UNC AS
           S. ARRCREW MAY FLY IRMEDIATELI.
           C. @l.iC'ilil SURGEONS WILL MONITOR   CLOSELY ALL AIRCREW TAKING
         PYRII)OSTIG14INE INCLUDIN14, AS FAR AS-POSS113I.E, DAILY CONTACT WITH'
         EACH (-r,[:14 Mt:.14BER.


         IMMEDIAR,E                      U N    L A S S I F I E D

Document 3 f:/Week-44/BX600093/FOLDER NAVAL MESSAGE FILES AUG OCT 90 ARMY REFERRAL/puridostigmine bromide pretreatment for nerve ag:01029709371915
Control Fields 17
File Room = oct96_declassified
File Cabinet = Week-44
Box ID = BX600093
Unit = COMUSMARCENT
Parent Organization = COMUSCINCCEN
Folder Title = FOLDER NAVAL MESSAGE FILES AUG OCT 90 ARMY REFERRAL
Folder Seq # = 34
Subject = PURIDOSTIGMINE BROMIDE PRETREATMENT FOR NERVE AG
Document Seq # = 5
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 02-JAN-1997