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File: 082696_doc1_089.txt
CAS Registry Number: 7784-42-1
Page 2 of 3
ARSINE
Signs and Symptoms of Acute Arsine Exposure:
Warning: Effects usually appear within 30 to 60 minutes, but may be delayed
for several hours. Caution is advised.
Note: Arsine is the most powerful hemolytic poison encountered in industry.
Acute arsine exposure may be fatal. Headache and a garlicky odor of the breath
may be the first signs and symptoms noted following acute exposure to arsine.
Victims may experience hypotension (low blood pressure), generalized weakness,
and muscle cramping. Gastrointestinal effects include nausea, vomiting,
anorexia, and abdominal pain. Urine may be colored red or green, and the
volume may be reduced. Arsine is corrosive to the skin, eyes, and mucous
membranes. Severe exposure may result in cardiac abnormalities.
Emergency Life-Support Procedures: we~ao~prntir:aitvi0encao:tdhilifCaSi:uprP0;Jiatoer toiC
Acute exposure to arsine may require
the type and degree of contamination. Victims must be transported to a health
care facility as quickly as possible. Air-purifying or supplied-air
respiratory equipment should also be worn, as necessary. Rescue vehicles
should carry supplies such as plastic sheeting and disposable plastic bags to
assist in preventing spread of contamination.
Inhalation Exposure:
I. Mooveavii:neims to fresh air. Emergency personnel should avoid self-exposure
2. RUSH to a health care facility!
3. Evaluate vital signs including pulse and respiratory rate, and note any
trauma. If no pulse is detected, provide CPR. If not breathing, provide
artificial respiration. If breathing is labored, administer oxygen or
other respiratory support.
4. Obtain authorization and/or further instructions from the local hospital
for administration of an antidote or performance of other invasive
procedures.
I)ermal/Eye Exposure:
1. Remove victims from exposure. Emergency personnel should avoid self-
exposure to arsine.
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