USAMRICD TECH MEMO 90 1 CLINICAL NOTES ON CHEM CASUALTY CARE

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Subject: USAMRICD TECH MEMO 90 1 CLINICAL NOTES ON CHEM CASUALTY CARE    

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003205

Folder Title: CLINICAL NOTES ON CHEMICAL CASUALTY CARE                                                        

Document Number:          1

Folder Seq  #:         31




           AUG 16 '90 11:46                                               P.21





           u     CD Technical Memorandum 90-1

                           coughing, dyapnea, secretions; necrotic mucosa in
                           airways with paeudomembrane formation
                     4. Systemic
                           a. Available data suggest an increase in
                           capillary permeability with fluid loss leading to
                           hemooonoontration and shook. There may be
                           hepatic and renal congestion/necroBis along with
                           gastrointestinal effects (vomiting, diarrhea)
                M. Treatment
                     1.    Immediate decontamination is a must if severe and
                           p @ anent damage is to be prevented, especially in
                           the eye
                     2.    Dinercaprol (British Anti-Lewisite; BAL) will bind
                           Lewisite and decrease its effects.   It should be
                           applied to the eye (BAL ophthalmic ointment) and
                           skin (BAL ointment) immediately after thorough
                           decontamination. It can also be given
                           systemically (BAL-in-oil) to reduce systemic
                           effects. BAL is not innocuous and one should be
                           aware of its side effects before using.
                     3.    Silver sulfadiazine might be used for topical care
                           (see mustard therapy) after lesions develop.
                           Should not be applied over BAL as it will
                           neutralize it. BAL should be applied early, as
                           soon as possible; sulfadiazine is for later care.
                     4.    Supportive care similar to that for mustard, with
                           particular attention to hypovolenia, shock
dimercaptosuccinic
                           acid), DMPS (2,3-dimarcapto-i-propanesulfonic
                           acid), and DMPA (N-(2,3-dimercaptopropyl)-
                           ghthalamidic acid) are in experimental stage and
                           may offer advantages over BAL.
                N. Long    term effects
                     1.    Fe data


           51. PROSGENE OXIME

                A.   Acronym is CX; very little biological data; do not
                     confuse with phosgene (CG)
                B.   Is an urticant or corrosive; causes immediate pain and
                     later necrosis of skin by vapor or as liquid
                C.   Has very disagreeable odor
                D.   Data lacking on vapor density, liquid density,
                     volatility
                E.   Toxicity (dogs; very little data)
                     Lethal by inhalation     1500--2000 mg/cu n
                     Lethal, percutaneous       25 mglkg
                F.   Mechanism of action--not reported
                C.   May be used in 'mixture; irritancy will cause mask
                     removal and greater exposure to second agent

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Document 22 f:/Week-36/BX003205/CLINICAL NOTES ON CHEMICAL CASUALTY CARE/usamricd tech memo 90 1 clinical notes on chem c:12249609312728
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003205
Unit = OTSG
Parent Organization = HSC
Folder Title = CLINICAL NOTES ON CHEMICAL CASUALTY CARE
Folder Seq # = 31
Subject = USAMRICD TECH MEMO 90 1 CLINICAL NOTES ON CHEM C
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 24-DEC-1996