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File: 970101_sep96_decls37_0020.txt
Subject: MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIAL
Unit: OTSG
Parent Organization: HSC
Box ID: BX003201
Folder Title: MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIAL
Document Number: 1001
Folder Seq #: 31
UNCLASSIFIED
s@y OF SECTION II
Avoidance by way of physical protection is the most
effective approach to biological warfare agent exposure-
Clinical recognition of symptoms and signs in mass
casualties may be the first indication of an attack. Patient
specimens (blood, urine) should not be a unique risk to medical
personnel, although vegetative anthrax, plague, or tularemia
organisms may be in blood.
PARALYSIS IN THE BW/CW SETTING
The differential diagnosis must include both botulinum and
nerve agent intoxications:
. Nerve agent is rapid in onset (minutes to 1-2 hours). A
rigid paralysis develops with parasympathetic excess
(salivation, miosis, sweating, involuntary defecation, and
urination); central nervous system dysfunction and death
soon follow. If exposure is by aerosol or vapor,
constricted pupils, rhinorrhea, and broncho constriction
also occur.
. Botulinum toxin is slower in onset (3 hours to several
days). Descending paralysis (bulbar to extremities to
respiratory) and parasympathetic blockade (dry mouth,
pupillary dilation, constipation, urinary retention, absence
of sweating) are characteristic. Paralysis, nausea,
vomiting, and diarrhea may, however, occur after exposure to
either nerve agent or botulinum toxin. Central signs
(confusion, seizure, coma) are rare after botulinum, but
common after nerve agent intoxication.
. Anticholinergics, such as atropine can, of course, cause
central nervous system changes such as agitation, confusion,
and hallucinations as well as dry mouth, dry skin, and
nges could easily obscure the
correct diagnosis in a soldier who used his injector even
without exposure to an agent.
17
UNCLASSIFIED
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Document 23 f:/Week-36/BX003201/MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIAL/medical defense against biological material:12249609313138
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003201
Unit = OTSG
Parent Organization = HSC
Folder Title = MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIAL
Folder Seq # = 31
Subject = MEDICAL DEFENSE AGAINST BIOLOGICAL MATERIAL
Document Seq # = 1001
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 24-DEC-1996