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File: 970107_sep96_decls9_0009.txt
Subject: USAMRIID SUPPORT OF OPERATION DESERT SHIELD
Unit: OTSG
Parent Organization: HSC
Box ID: BX003202
Folder Title: USAMRIID BRIEFING TO BG BLANCK-BGJUMPER-RADM SMYTH
Document Number: 500001
Folder Seq #: 500000
Equine Antibotulinum Plasma:
Protocol Summary
PROTOCOL TO PRODUCE QUADRAVALENT PLASMA:
Monovalent (one per horse) serotypes: A, B, E & F
Compressed Immunization schedule: 0, 3 & 7 weeks
Intensive Bleeding schedule: begin at 9 weeks
18 Feb 91--First bleeds (serotype B)
11 Mar 91--Bleeding started on all serotypes
48 Horses ---- 2,880 liters plasma/month ---- 24,000 doses (Fab'2)
ANTIGENS (TOXOID & TOXIN):
A= From MDPH
5.0 liters or 10,000 human doses--First and second dose
B= From MDPH
6.0 liters or 12,000 human doses--First and second dose
E= From USAAMHD stocks
1.0 liters or 2000 human doses ---- First dose for 6 horses
F= From the UK
2.4 liters or 4800 human doses ---- First and second dose
Subsequent toxoid and toxin from USAMRIID
Purification of toxin (A, B & E) for boosts
Additional toxin production/procurement (F)
EVALUATION OF IMMUNE RESPONSE OF HORSES:
Mouse neutralization tests ----- ca. 75,000 mice/year
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Document 12 f:/Week-36/BX003202/USAMRIID BRIEFING TO BG BLANCK-BGJUMPER-RADM SMYTH/usamriid support of operation desert shield:01029715470910
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003202
Unit = OTSG
Parent Organization = HSC
Folder Title = USAMRIID BRIEFING TO BG BLANCK-BGJUMPER-RADM SMYTH
Folder Seq # = 500000
Subject = USAMRIID SUPPORT OF OPERATION DESERT SHIELD
Document Seq # = 500001
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 02-JAN-1997