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Knoke, J.D. and Gray, G.C. Hospitalizations for Unexplained Illnesses among U.S Veterans of the Persian Gulf War. Emerging Infectious Diseases 1998; 4: 211-219.

The authors compared the postwar hospitalization records of active duty GW veterans and active duty GW-era veterans (up to 1 April 1996) for one or more of 77 diagnoses under the ICD-9 system. The diagnoses were assembled by the Emerging Infections Program, Centers for Disease Control and Prevention, and are termed "unexplained illnesses." Deployed veterans were found to have a slightly higher risk of hospitalization for unexplained illness than the nondeployed. Most of the excess hospitalizations for the deployed were due to the diagnosis "illness of unknown cause" (ICD-9 Code 799.9), and most occurred in participants in the Comprehensive Clinical Evaluation Program who were admitted for evaluation only. When the effect of participation in this program was removed, the deployed had a slightly lower risk than the nondeployed. These findings suggest that active duty GW veterans did not have excess unexplained illnesses resulting in hospitalization in the 4.67 year period following deployment. Limitations: many personnel separated from the service during the period of follow-up (59.8% of the deployed and 54.3% of the nondeployed); time and geography-specific exposures could not be examined; and, illnesses not serious enough to require hospitalization may not have been captured.

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