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File: 102496_sep96_decls3_0008.txt
Page: 0008
Total Pages: 9

Subject: MEDICAL BRIEF SUMMARIES                                         

Unit: OTSG        

Parent Organization: HSC         

Box ID: BX003202

Folder Title: BRIEFING TO BG BLANCK BOTULINUM TOXOID                                                          

Document Number:          1

Folder SEQ  #:         12


    SENT BY:USAMRIID                      7-91 ; 10:00               SaRD-UIA-A-           5-7037560121;# 8





                                  @-BO@                  EQ@ F(ab')2


           o First horses delivered                                     14 December 1990

           a  52 now horses available                                   15 December 1990

           0  Draft SOW for plasma processing contract                  16 December 1990

           a  Phys,@cals completed; 6 horses immunized                  17 December 1990

           t  12 horses immunized                                       21@ December 1990

           4, i-ninunize 24 horses                                      7-9 January 1991

           e  Immunize 6 horses                                         10-22 January 1991

           a  Contract award for plasma processing                      15 February 1991

           t  First bleeds of lst group of horses                       18 February 1991
           *  Initiate plasma processing                                late February 1991

           4  Initiate bleeds of all horses                             11 March 1991

              Plasma processing (2 wks/batcli)                          Apr/May 1991

              Test first lots/IND                                       May/June 1991

              Product available                                         Junel991


           ISSUES:

           , Rapid immunization - risks unknown in terms of product characteristics and
           availability.

              Product formulation different from IND submission.

              Immunization of additional horses if current animals fail to respond - impact
           on antigen availability for immunization and time to product.

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Document 9 f:/Week-36/BX003202/BRIEFING TO BG BLANCK BOTULINUM TOXOID/medical brief summaries:1011961539064
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003202
Unit = OTSG
Parent Organization = HSC
Folder Title = BRIEFING TO BG BLANCK BOTULINUM TOXOID
Folder Seq # = 12
Subject = MEDICAL BRIEF SUMMARIES
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 11-OCT-1996