TRI SERVICE VACCINE TASK FORCE 7 DEC 90

File: 102596_sep96_decls2_0001.txt
Page: 0001
Total Pages: 8

Subject: TRI SERVICE VACCINE TASK FORCE 7 DEC 90                         

Unit: OTSG        

Parent Organization: HSC         

Box ID: BX003202

Folder Title: DESERT SHIELD MEDICAL ISSUES REVIEW AND AD HOC WORKING GROUP                                    

Document Number:          3

Folder SEQ  #:         31





                                                      UNCLASSIFIED
                                DEPARTMENT OF THE ARMY
                               WALTER FTEED ARMY INSTFTUTE OF RE@CH
                                 WALTER AEED ARA(Y #AEWAL CENTER
                                    WASHINGTON. D.C. @-SIW




            M FW-PLY AEFER Ta.

        SGRD-UWZ-H                                     7 December 1990


        MEMORANDUM THRU Commander, USA Medical Research and Development
                            Command, Fort Detrick, Frederick, Maryland
                            21701-5012

        FOR The Surgeon General, 5109 Leesburg Pike, Falls Church, VA
               22041-3258

        SUBJECT: Tri-Service Vaccine Task Force (Appendix A)


        BACKGROUND:

        1. Diarrheal diseases have always been significant military
        problems in Middle East campaigns (e.g. WWI, Gallipoli; WWII, El
        Alamein; Suez crisis, UK, 1956; Lebanon, USA, 1957 and 1983;
        Israeli Defense Force, 1966, 1972, 1983) and have been implicated
        as cont-ribilitina determinants of victory (Rats, Lice and History,
        H. Zinsser, c i939 Little-Brown, Co. Boston, MA). Diarrheal
        diseases have already proven problematic in Desert Shield and
        with the increasing likelihood of a continued U.S. presence, are
        destined to become an even greater problem (Appendix B).
        Furthermore, resistance to ciprofloxacin, the only currently
        effective antibiotic to treat shigellosis, is predicted to occur
        within 12-16 months (Appendix B).

        2. Hepatitis A is transmitted by the    fecal-oral route and
        follows the same epidemiologic pattern as diarrheal diseases.
        Hepatitis A was a significant problem for U.S. troops in the
        North African campaign in WWII and is a persistent problem for
        the Israeli Defense Force. Hence, our policy of prophylaxis with
        Immune Serum Globulin. However, this requires repeated
ery three months and is an inadequate long termi
        strategy (Appendix C).

        3. Post wounding sepsis in modern warfare has become a major
        cause of morbidity, mortality and cost. Hence, a USAMRDC mission
        has been to develop vaccines against the major causes of post
        wounding sepsis. Because of the difficulty in performing the
        appropriate human studies, the approach taken has been to first
        demonstrate efficacy by producing hyperimmune antisera and human
        monoclonal antibodies and then fashion the antigen into a
        vaccine. The individual vaccines are in various stages of
        development (Appendix D).

                                             EDMUND C. TRAMONT, COL, MC
        Declassified per SECARMY by CMH: 10-1 5-1996

Document 8 f:/Week-36/BX003202/DESERT SHIELD MEDICAL ISSUES REVIEW AND AD HOC WORKING GROUP/tri service vaccine task force 7 dec 90:1018961354253
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003202
Unit = OTSG
Parent Organization = HSC
Folder Title = DESERT SHIELD MEDICAL ISSUES REVIEW AND AD HOC WORKING GROUP
Folder Seq # = 31
Subject = TRI SERVICE VACCINE TASK FORCE 7 DEC 90
Document Seq # = 3
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 18-OCT-1996