RECOMMENDATION CONCERNING USE OF CIPROFLOXACIN 17 DEC 90

File: 120396_sep96_decls29_0001.txt
Page: 0001
Total Pages: 2

Subject: RECOMMENDATION CONCERNING  USE OF CIPROFLOXACIN  17 DEC 90      

Unit: OTSG        

Parent Organization: HSC         

Box ID: BX003203

Folder Title: RECOMMENDATION FOR THE USE OF CIPROFLOXACIN                                                     

Document Number:          1

Folder SEQ  #:         42




                                                     UNCLASSIFIED


                               DEPARTMENT OF    DEFENSE
                           ARMED FORCES EPIDEMIOLOGICAL BOARD
                                   5109 LEESBURG PIKE
                                FALLS CHURCH, VA22041-3258


         AFEB (15-1a)                                        17 December 1990


         MEMORANDUM FOR THE ASSISTANT SECRETARY OF DEFENSE (HEALTH AFFAIRS)
                         THE SURGEON GENERAL, DEPARTMENT OF THE ARMY
                         THE SURGEON GENERAL, DEPARTMENT OF THE NAVY
                         THE SURGEON GENERAL, DEPARTMENT OF THE AIR FORCE

         SUBJECT: [U] Recommendation Concerning the Use of Ciprofloxacin

         1. On 14 December 1990 appropriate members of the Disease Control
         Subcommittee of the Armed Forces Epidemiological Board were
         requested by the Surgeon General, Department of the Army (SGSP-
         PSP), to consider the use of Ciprofloxacin as an adjunct in
         countering the threat of inhalation anthrax. The basic request is
         provided at enclosure (1). Dr. Theodore E. Woodward, Dr. Abram S.
         Benenson, and Dr. Scott B. Halstead met with appropriate service
         representatives on 17 December 1990 to review existing information
         and the proposed application of Ciprofloxacin.

         2.   Based on the data presented and subsequent discussions the
         Board:

              a.   Concurs with the use of Ciprofloxacin as an adjunct
         countermeasure against inhalation anthrax. The doctrine for use is
         understood to be as follows:

                 (1) All service members will be issued a blister pack of
         ten Ciprofloxacin tablets (500mg) with instructions to take one
         tablet every 12 hours. The decision to begin taking the antibiotic
         will be made by the tactical commander.

                 (2)   If potential exposure to anthrax is confirmed the
 at least one anthrax vaccine booster
         immunization and be provided with sufficient Ciprafloxacin to be
         taken for 30 days. Should suspicious clinical symptoms occur the
         service member will be treated with oral Ciprofloxacin (1000 mg
         loading dose followed by 750 mg twice daily), intravenous
         doxycycline (200 mg loading dose followed by 100 mg two times
         daily) , or other appropriate antibiotics based on bacterial
         sensitivity testing.

              b.  Strongly recommends that specimens be cultured, identified
         and tested for antibiotic sensitivity utilizing resources available
         in-theatre.   It is considered essential that this information be
         available without delay to determine preventive measures and permit
                                         DECLASSIFIED
         CLASSIFIED BY: MULTIPLE SOURCEGN: 04 NOV 96
         DECLASSIFY BY: OASD                        MY (DAMH) UNDER SEC 3.4 EO 12958
                                   a
                    UNCLASSIFIE@

Document 2 f:/Week-36/BX003203/RECOMMENDATION FOR THE USE OF CIPROFLOXACIN/recommendation concerning use of ciprofloxacin :11089615091630
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003203
Unit = OTSG
Parent Organization = HSC
Folder Title = RECOMMENDATION FOR THE USE OF CIPROFLOXACIN
Folder Seq # = 42
Subject = RECOMMENDATION CONCERNING USE OF CIPROFLOXACIN
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 08-NOV-1996