RECOMMENDATION CONCERNING THE USE OF CIPROFLOXACIN

File: 970101_sep96_decls32_0001.txt
Page: 0001
Total Pages: 2

Subject: RECOMMENDATION CONCERNING THE USE OF CIPROFLOXACIN              

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003201

Folder Title: RECOMMENTATION CONCERNING THE USE OF CIPROFLOXACIN                                              

Document Number:       1001

Folder Seq  #:         22


                                                                    6@c @P
                                     UNCLASSIFIED



                              DEPARTMENT OF    DEFENSE
                         ARMED FORCES EPIDEMIOLOGICAL BOARD
                                  5109 LEESBURG PIKE
                              FALLS CHURCH, VA22041-3258               4
                                                                       .

         AFEB (15-1a)                                      17 December 1990


         MEMORANDUM FOR THE ASSISTANT SECRETARY OF DEFENSE (HEALTH AFFAIRS)
                        THE SURGEON GENERAL, DEPARTMENT OF THE ARMY
                        THE SURGEON GENERAL, DEPARTMENT OF THE NAVY
                        THE SURGEON GENERAL, DEPARTMENT OF THE AIR FORCE

         SUBJECT: [U] Recommendation Concerning the Use of Ciprofloxacin

         1. On 14 December 1990 appropriate members of the Disease Control
         Subcommittee of the Armed Forces Epidemiological Board were
         requested by the Surgeon General, Department of the Army (SGSP-
         PSP), to consider the use of Ciprofloxacin as an adjunct in
         countering the threat of inhalation anthrax. The basic request is
         provided at enclosure (1). Dr. Theodore E. Woodward, Dr. Abram S.
         Benenson, and Dr. Scott B. Halstead met with appropriate service
         representatives on 17 December 1990 to review existing information
         and the proposed application of Ciprofloxacin.

         2.  Based on the data presented and subsequent discussions the
         Board:

             a.   Concurs with the use of Ciprofloxacin as an adjunct
         countermeasure against inhalation anthrax. The doctrine for use is
         understood to be as follows:

                (1) All service merabers will be issued a blister pack of
         ten Ciprofloxacin tablets (500mg) with instructions to take one
         tablet every 12 hours. The decision to begin taking the antibiotic
he tactical commander.

                (2)   If potential exposure to anthrax is confirmed the
         service member must receive at least one anthrax vaccine booster
         immunization and be provided with sufficient Ciprofloxacin to be
         taken for 30 days. Should suspicious clinical symptoms occur the
         service member will be treated with oral ciprofloxacin (1000 mg
         loading dose followed by 750 mg twice daily), intravenous
         doxycycline (200 mg loading dose followed by 100 mg two times
         daily), or other appropriate antibiotics based on bacterial
         sensitivity testing.

            b.   Strongly recommends that specimens be cultured, identified
         and tested for antibiotic sensitivity utilizing resources available
         in-theatre. It is considered essential that this information be
         available without delay to determine preventive measures and permit


         CLASSIFIED BY: MULTIPLE SOURCES
         DECLASSIFY BY: OASD
                                  OA                 UNCLASSIFIED

       DECLASSIFIED
       ON: 12 DEC 96
       BY: SEC ARMY (DAMH) UNDER SEC 3.4 EO 12958

Document 2 f:/Week-36/BX003201/RECOMMENTATION CONCERNING THE USE OF CIPROFLOXACIN/recommendation concerning the use of ciprofloxac:12249609312933
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003201
Unit = OTSG
Parent Organization = HSC
Folder Title = RECOMMENTATION CONCERNING THE USE OF CIPROFLOXACIN
Folder Seq # = 22
Subject = RECOMMENDATION CONCERNING THE USE OF CIPROFLOXAC
Document Seq # = 1001
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 24-DEC-1996