COVER SHEET FOR DOCUMENT TRANSMISSION

File: 970107_sep96_decls61_0005.txt
Page: 0005
Total Pages: 7

Subject: COVER SHEET FOR DOCUMENT TRANSMISSION                           

Unit: OTSG        

Parent Organization: HSC         

Box  ID: BX003205

Folder Title: 4TH USAMRDC LEISHMANIASIS VARIOUS LEVELS                                                        

Document Number:          1

Folder Seq  #:         12



                             Sym"oms reported following 720 FU vaccine:

                                      symiptom   No.   PercenL
                                      Fever      289      2.1
                                      Headache   289     13.8
                                      Malaise             9.7

                             (2) Conclusions

                                (a) The higher potency vaccine appears to provide
                                all recipients with antibody following a 0, 14 day
                                schedule.

                                (b) Antibody persists for at least 9 months.

                                (c) The comparability of this data to data
                                collected at Ft. Campbell is unknown, since
                                different populations and differents assays were
                                used.

                                (d) Assessment of this schedule in U. S. Soldiers
                                should be carried out immediately.

                      3. Availability of vaccine

                      The company provided the following figures on 5 December
                      1990.

                                Availability of SKB HAV vaccine (HAVRIX)*

                      Number of Available         Soldiers
                      doses        Date           Protected   Cost
                        80,000     15 DEC 90      40,000      $0.8m
                        80,000     30 JAN 91      40,000      $0.8m
                      500,000       1 MAY 91     250,000      $5.OM
                                                 330,000      $6.8

                        Availability subject to passing final safety tests.

                      Thus, a large portion of the force in Saudi Arabia could be
                      immunized against hepatitis A for approximately $ 7
                      million.

                      4. WRAIR research plans

on the use of rapid immunization schedules with the
                      higher potency vaccine in soldiers is required. A study is
                      planned to be carried out at Schofield Barracks in February
                      1991. The 25ID Division Surgeon, LTC Steve Jones, had
                      provided substantial support before this became an urgent
                      matter. we would expect continued excellent support.

                      S. Other considerations

                         a. Alternatives

                             (1) Immune serum globulin

                             ISG is considerably cheaper. Disadvantages include
                             its limited supply as a licensed product and the


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Document 7 f:/Week-36/BX003205/4TH USAMRDC LEISHMANIASIS VARIOUS LEVELS/cover sheet for document transmission:01029715474762
Control Fields 17
File Room = sep96_declassified
File Cabinet = Week-36
Box ID = BX003205
Unit = OTSG
Parent Organization = HSC
Folder Title = 4TH USAMRDC LEISHMANIASIS VARIOUS LEVELS
Folder Seq # = 12
Subject = COVER SHEET FOR DOCUMENT TRANSMISSION
Document Seq # = 1
Document Date =
Scan Date =
Queued for Declassification = 01-JAN-1980
Short Term Referral = 01-JAN-1980
Long Term Referral = 01-JAN-1980
Permanent Referral = 01-JAN-1980
Non-Health Related Document = 01-JAN-1980
Declassified = 02-JAN-1997