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Perceived Exposure to Chemical Weapons and Unexplained Illness Among Military and Civilian Subjects

Peter S. Spencer, W. Kent Anger, Linda A. McCauley, Elizabeth Esseks

Portland Environmental Hazard Research Center (PEHRC) and L
Umatilla-Area Health Research Planning Group

Belief of exposure to chemical weapons is a prominent and persistent characteristic of a randomly sampled group of Northwestern veterans who served in the Gulf War and who currently have unexplained health symptoms. Not only is this belief reported by veterans who served during or following Desert Storm -- when releases of mustard and nerve agents are known to have occurred at Khamisiyah and elsewhere, but also by approximately 30% of sampled veterans who served in Desert Shield and who left Southwest Asia before the conflict began. In parallel fashion, several symptomatic Japanese civilians who believed they had sustained exposure to sarin following release of nerve agent in a Tokyo subway were found on examination to have no overt evidence of exposure. A unique and short-lived opportunity to examine this apparent paradox is provided by the pending incineration of stockpiled nerve and mustard agents at the U.S. Army Ordnance Depot, Umatilla, Oregon, and other U.S. weapons-incineration sites with sizeable proximate communities. Study of these cohorts prior to, during, and following weapons incineration allows prospective examination of the health impact of proximity to this novel process. Under planned operating conditions, populations would be exposed to undetectable concentrations of nerve and mustard agents, with minimal exposure to the combustion products thereof. Longitudinal comparison of the health of impacted populations relative to that of equivalent rural populations without proximity to weapons incineration offers an objective scientific method to assess the evolution, temporal prevalence, and nature of the health phenomenon associated with perceived exposures. It also provides an opportunity to develop and implement chemical, biological, psychological, neurobehavioral and other methods to measure potential exposures and health effects. Moreover, examination of human populations close to weapon-incineration sites establishes a foundation on which to assess health effects in the unlikely event of an unplanned release of agents sufficient to cause exposures resulting in short-term or delayed toxicity. In sum, there is an unparalleled opportunity to develop and implement research-based health monitoring of military and civilian populations at risk for illness associated with perceived or actual exposures to chemical weapons.

"Keywords:" Chemical weapons Perceived risk Health symptoms

This work was supported by a grant from the Department of Veterans Affairs to the PEHRC, a joint project of the Portland Veterans Affairs Medical Center and the Center for Research on Occupational and Environmental Toxicology, Oregon Health Sciences University.

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